HF1481

YKL-5-124

English Name: YKL-5-124
English Alias: s8863;N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[[4-(prop-2-enoylamino)benzoyl]amino]-1,4-di
CAS No.: 1957203-01-8
Molecular Formula: C28H33N7O3
Molecular Weight: 515.61
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YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays biochemical and cellular selectivity for CDK7 over CDK12/13.

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